CORRELATION STATUS OF VITAMIN D WITH EARLY ONSET PREECLAMPSIA

Dian Siregar, Hotma P Pasaribu, Risman F Kaban, Henry Siregar, M Fahdhy, Riza Rivany

Abstract


Background: Preeclampsia is one of the contributors to the causes of maternal and child mortality in the world, WHO notes preeclampsia occurs with an incidence of 3-10% of all pregnancies, whereas early onset preeclampsia affects about 7% of all cases of preeclampsia. Vitamin D status is often associated with poor pregnancy outcomes, especially in preeclampsia.

Objective: To determine the relationship between Vitamin D status reflected by serum 25-hydroxyvitamin D levels and the incidence of early onset preeclampsia.

Method: This study is a case control analytic that compares the total plasma levels of 25-hydroxyvitamin D serum in normal pregnancies <34 weeks and cases of early onset preeclampsia. Characteristics of the study subjects and vitamin D levels were collected on each subject. Levels of plasma 25-hydroxyvitamin D are reported in nanograms per milliliter. To analyze the relationship between Vitamin D levels, an independent T test was performed and Chi Square test at a significance level of 5% (p <0.05).

Results: This study is a case control analytic that compares the total plasma levels of 25-hydroxyvitamin D serum in normal pregnancies <34 weeks and cases of early onset preeclampsia. Characteristics of the study subjects and vitamin D levels were collected on each subject. Levels of plasma 25-hydroxyvitamin D are reported in nanograms per milliliter. To analyze the relationship between Vitamin D levels, an independent T test was performed and Chi Square test at a significance level of 5% (p <0.05).

Conclusion: Vitamin D deficiency is associated with an increased risk of early onset preeclampsia

 


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References


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