FINE NEEDLE ASPIRATION CYTOMORPHOLOGICAL SPECTRUM (FNAC) OF PERIPHERAL LYMPH NODE LESIONS AT A TERTIARY CARE TEACHING MEDICAL COLLEGE & HOSPITAL

Anand Ashok Bhosale, Sithy Athiya Munavarah, N Jeybalan

Abstract


Introduction: Peripheral lymhadenopathy is common presentation of inflammatory and neoplastic lesions.FNAC is one of the first-line investigations of managenent for the evaluation of lymphadenopathy.Enlargement of Lymph node is seen in variety of reactive inflammatory to neoplastic conditions related to regional or systemic diseases. It is very useful, easy, rapid, minimal invasive, cost effective and accurate approach in diagnosing various lymph node lesions and helpful in the workup of management of patients with nodal enlargement. Methods: A total of 175 patients were included in our study Department of Pathology,  referred from the department of ENT, Medicine, Paediatrics, Surgery, Respiratory Medicine and Tuberculosis of Karpaga Vinayaga Hospital in the period from January 2017 to Dec 2018. Alcohol fixed and air dry smears were prepared and stain with H&E, PAP, and MGG. The special stain like PAS, ZN (20%) etc were done whenever required. Results:In present study total 175 cases of lymphadenopathy were studied. The presentation of various lymph node lesions on cytomorphological findings were Acute non-specific lymphadenitis cases were 5 (2.85%), Chronic non-specific lymphadenitis cases were 11 (8.28%), Granulomatous lymphadenopathy cases were 6 (3.42%), Tuberculous lymphadenitis cases were 60 (34.28%)’ Reactive lymphadenitis cases were 48 (27.42%), Metastasis to lymph node cases was 36 (20.57%), Lymphoma cases were 9 (5.14%). Unsatisfactory smears(11) were excluded from the study. The detailed clinical material data, relevant investigations were taken for supporting the diagnosis. Conclusion: Cytomorphological features of lymph node FNAC, used in conjunction with clinical details, laboratory test investigations, radiology imaging study will be very helpful for diagnosing various disorders. It will be rapid, cost effective, safe, and reliable method for early diagnosis and treatment of the patients

 


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References


Dr. Vatsala Sharma, Dr. Parveen Shah, Dr. (Brig) Vinod Raghava, Dr. Uma Sharma, Cytomorphological Spectrum of Lymph Node Swellings:A Tertiary Care Hospital Study in Gurugram; IOSR-JDMS; 2279-0853,Volume 17, Issue 1 Ver. 13 January. (2018), PP 56-59

Caroline W. Cells, Tissues and systems. In: Susan S, editor. Gray’s anatomy, 40th ed. London: Churchill Livingstone; 2009. P. 6680.

Ioachim HL, Medeiros JL. Ioachim’s lymph node pathology, fourth edition, Lippincott Williams Wilkins, 2008.

Orell SR, Sterer GF, Whitaker D. Fine needle aspiration cytology, 4th edition, Chirchill Livingston, 2005; 1-8 and 83-124.

Hemalatha A, Udaya Kumar M, Harendra Kumar ML. Fine needle aspiration cytology of Lymph nodes: a mirror in the diagnosis of spectrum of lymph node lesion. J Clin Biomed Sci 2011;1,4:164-72.

Khillan R, Sidhu G, Abiotic C, et al. Fine needle aspiration cytology for diagnosis of cervical lymph adenopathy. Int J Hematol. 2012. 95:282-284.

Zeepa P, Marino G, Troncone G, et al. Fine needle cytology and flow cytometry, immunophenotyping and subclassification of non-hodgkinlymphoma: a critical review of 307 cases with technical suggestion. Cancer, 2004.102:55-65.

Sunil Vitthalrao Jagtap1, Swati Sunil Jagtap2, Vidya Chandrashekhar Aher, Ritvik Sanjay Khandelwal, Spectrum of Lymph Node Lesions on Fine Needle Aspiration Cytology: Study of 187 Cases at Tertiary Care Hospital, Int J Health Sci Res. 2015; 5(11):111-114

Paul PC, Goswami BK, Chakrabarty, et al. Fine needle aspiration cytology of lymph nodes- an institutional study of 1448 cases over five years period. J Cytology.2004;21:187-90.

Khajuria R, Gosswami KC, Singh K, et al. Pattern of lymphadenopathy on fine needle aspiration cytology in Jammu. JK Science,2006;8,3:157-159.

Bhaskaran CK, Kumar HG, Sreenivas M, et al. Fine needle aspiration cytology, review of 1731 cases. Indian J Pathol Microbiol.1990;33:387-99.

Gupta RK, Naran S, Lallu S, et al. The diagnostic value of fine needle aspiration cytology in assessment of supraclavicular lymph node: a study of 218 cases. Cytopathology, 2003; 14: 201-7.

Ghartimagar DG, Ghosh A, Ranabhat S, et al. Utility of fine needle aspiration cytology in metastatic lymph nodes. Jr of Pathology Nepal. 2011;1:92-5.

Patel MM, Italiya SL, Dhandha ZB, et al. Study of metastasis in lymph nodes in Fine needle aspiration cytology: our institutional experience review. International Journal of Research in Medical Sciences. 2013;1,4:451-4.

Khan AH, Hayat AS, Baloch CH, et al. Study of fine needle aspiration

cytology in cervical lymphadenopathy. World Appied Sciences Journal. 2011;12(11):1951-54.

Javed M. Diagnostic value of fine needle aspiration cytology in cervical lymphadenopathy. J Postgrad Med Inst. 2006;20(2):117-20.


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