A CLINICAL STUDY OF ESTROGEN AND PROGESTERONE RECEPTORS STATUS AND CLINICAL STAGE OF CARCINOMA BREAST PATIENTS IN UPPER ASSAM ( A PROSPECTIVE STUDY)

Dr. Abhinav Puri, Dr. Bijoyananda Das

Abstract


Introduction: Carcinoma breast is the most common cancer in women worldwide. But mortality is decreasing due to early detection by active screening program and better understanding of receptors status and treatment following results of receptors status. But in India patients usually presents in later stage due to lack of awareness and active screening program . so BCS is not possible and MRM is the treatment of choice along with neoadjuvant chemotherapy which cause more morbidity.

Method and material: study was conducted in Assam medical college and hospital from june 2017 to January 2018 and patients followed by a variable period of 3 to 6 months. Cases was diagnosed and treated according to stage of their carcinoma.

Results: mean age of presentation is 43.11 yrs. Most common stage at presentation stage 3a(38.24%) and stage 2b(35.29%). ER receptors positivity is 50%. HER-2/neu positivity is 47%. Triple positive 23.53% and triple negative 11.76%.

Conclusion: Receptors status should be done in all cases then hormonal / targeted therapy should be started which improves survival . In India average age for presentation is a decade earlier then western countries so we should start an active screening program which should start at 35 yrs of age

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