CLINICO-EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH GYNAECOLOGICAL MALIGNANCIES BEING FOLLOWED-UP AT A RADIATION ONCOLOGY DEPARTMENT OF A TERTIARY CARE GOVERNMENT INSTITUTE OF INDIA

Nilotpal Chakravarty, Virender Suhag, Sunita B S

Abstract


Background: Gynaecological malignancies constitute a major burden of cancer-related morbidity and mortality amongst females in developing countries including India.

Aims and objectives: The study was conducted to study the clinical and morphological characteristics of patients having gynaecological malignancies and treated by radiotherapy with or without chemotherapy, now under follow-up.

Study design: A retrospective observational study in a tertiary care hospital of government set-up over 2 year period.

Observations: A total of 3120 patients who reported for follow-up were included, of which 394 patients were of gynaecological malignancies. Carcinoma (Ca) Cervix followed by Ca endometrium were the most common sites (76% and 16% respectively). The most common age group was 7th decade. 33% patients with locally advanced cervical cancer were found to have paraaortic lymphadenopathy on presentation warranting extended field radiotherapy (RT). 73% of locally advanced ca cervix patients received 5 or more cycles of weekly chemotherapy (CT) with Cisplatin.  68% patients were disease-free at the time of follow-up. 11% patients were referred for palliative chemotherapy. 17% patients required hospitalization for symptomatic care during followup.

Conclusion: Concurrent chemoradiation is an acceptable and well-tolerated modality of treatment for locally advanced gynaecological malignancies. Multimodal treatment and good collaboration between allied specialists is recommended.


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